Microplate Lids
Beckman Coulter Environmental Lid, Sterile, 10/pk
Environmental Lid minimizes edge effects and preserves the concentrations of solutions in microplate wells.
Cayman Chemical LeukotrIen C4 EIA Stndard 1ea
An antagonist of NR2B subunit-containing NMDA receptors (Ki 72 nM) selective for NR2B subunit-containing NMDA receptors over those containing NR2A subunits (IC50s 47 and 10000 nM respectively) reduces carrageenan-induced hyperalgesia in rats (ED50 5.5 mg/kg) reduces dopaminergic neuron loss in the rat substantia nigra pars compacta and improves measures of ipsilateral curling ipsilateral head positioning and beam walking in a rat model of 6-OHDA-induced Parkinsons disease at 10 mg/kg
Cayman Chemical IgG1humn ELISA Stndard 1ea
A phospholipid-porphyrin conjugate LNPs containing 1-palmitoyl-2-pyropheophorbide a-sn-glycero-3-PC and encapsulating FAM-labeled siRNA increase cytosolic siRNA levels 1-palmitoyl-2-pyropheophorbide a-sn-glycero-3-PC-stabilized nanoemulsions loaded with paclitaxel and combined with laser irradiation reduce tumor growth and increase survival in a KB squamous cell carcinoma mouse xenograft model
Cayman Chemical ResorufIn Stndard 100uL
Immunoassay Buffer C Concentrate (10X) has been formulated and tested to work with Cayman’s Assay Kits. Detailed instructions for its use are contained in the respective Cayman Assay Kit booklet.
Cayman Chemical Stndard DIluent asy Reagen 4mL
A multi-kinase inhibitor inhibits FLT3 CSF1R c-Kit FGFR1 FGFR3 VEGFR1 -2 and -3 PDFGRa and PDGFRB (IC50s 1 36 2 8 9 10 13 8 27 and 210 nM respectively) inhibits the proliferation of human multiple myeloma cell lines expressing mutant but not wild-type FGFR3 (IC50s 90-550 and >2500 nM respectively) decreases FGF-induced ERK1/2 phosphorylation and induces apoptosis in patient-derived multiple myeloma cells at 500 nM inhibits bFGF-induced angiogenesis in a Matrigel™ plUG assay in mice at 3-300 mg/kg for 8 days reduces tumor growth in KM12L4A DU145 and MV4-11 mouse xenograft models (ED50s 17 23 and 3 mg/kg per day respectively)
Cayman Chemical pNA Stndard 50uL
A riboside form of nicotinamide a precursor of NAD and a source of vitamin B3 increases intracellular and mitochondrial NAD content in C2C12 Hepa1.6 and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1000 M decreases acetylation of FOXO1 and SOD2 but not tubulin increases NAD levels in liver and skeletal muscle and prevents body weight gain in mice fed a high-fat diet when used at a dose of 400 mg/kg per day increases NAD in the cerebral cortex and reduces cognitive deterioration in a transgenic mouse model of Alzheimers disease
Chemglass Life Sciences Microplate, 24-Well Deep Well, 16 mL V-Bottom (Sterile, Nest-Pack, Includes Comb)
Chemglass deep-well 24-well microplate with 16 mL V-bottom wells, provided sterile and nest-packed for laboratory sample processing and storage. Includes a 24-well plastic comb and is suitable for automated workflows.
- 24 wells
- 16 mL nominal volume per well
- V-bottom well geometry
- Square well top for secure sealing
- Manufactured from USP Class VI polypropylene
- Sterile, nest-packed format
- Includes a 24-well plastic comb
- Suitable for storage, extraction, and automated processing
Cayman Chemical HydroxyprolIn Stndard 100uL
A derivative of NAD has been used in the determination of PARP target proteins a synthetic intermediate in the synthesis of cADPR derivatives
Cayman Chemical 96-Wel Cover Sheet 5ea
A multi-kinase inhibitor selectively inhibits MET VEGFR2 Axl and Mer (IC50s 3 15 5.8 and 0.6 nM respectively) over serine/threonine kinases for which it has no activity but does inhibit 28 additional RTKs (IC50s 3-54 nM) and additional kinases by greater than 70 at 1 UM inhibits the proliferation of SNU-5 cells (IC50 98.9 nM) and HUVECs (IC50 10.4 nM) reduces tumor volume and intratumoral MET phosphorylation in NCI H441 and SNU-5 mouse xenograft models at 3 and 10 mg/kg increases the number of peripheral B cells and CD4 T cells and decreases the number of peripheral myeloid cells in an MC-38 syngeneic mouse model of colon carcinoma at 30 mg/kg
Cayman Chemical CyclIc GMP ELISA Stndard 1ea
An ionizable cationic lipidoid has been used in the generation of LNPs LNPs containing AA-T3A-C12 and encapsulating Hsp47 siRNA reduce the expression of Hsp47 in activated NIH3T3 mouse liver fibroblasts and primary mouse hepatic stellate cells LNPs containing AA-T3A-C12 and encapsulating Hsp47 siRNA reduce CCl4-induced liver fibrosis in mice
Cayman Chemical 20HETEd6 MaxSpec Stndard 10ug
A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications